Effects of Pomegranate Juice on Ulcerative Colitis
NCT07115862 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2025-12-09
Summary
The purpose of this study is to determine whether consumption of 237 ml of pomegranate juice daily for 8 weeks will:
1. lower inflammation (in the gut as well as generally in the body) and improve your overall quality of life
2. affect the microbes living in the gut (gut microbiota)
Conditions
- Ulcerative Colitis (Disorder)
Interventions
- OTHER
-
pomegranate juice -> habitual diet
237 ml of pomegranate juice for the first 8 weeks -\> habitual diet for the second 8 weeks
- OTHER
-
habitual diet -> pomegranate juice
habitual diet for the first 8 weeks -\> 237 ml of pomegranate juice for the second 8 weeks
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
collaborator NIH -
University of California, Los Angeles
lead OTHER
Principal Investigators
-
Zhaoping Li, MD, PhD · University of California, Los Angeles
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-15
- Primary Completion
- 2027-10-15
- Completion
- 2027-10-15
Countries
- United States
Study Locations
More Related Trials
-
Cranberry and Gut Health in Crohn's Disease
NCT07170462 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Immune Regulation in Ulcerative Colitis or Crohn s Disease
NCT00001184 ·Status: RECRUITING
-
The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
NCT03615690 ·Status: RECRUITING ·Phase: NA
-
Broccoli Sprouts for Mild Ulcerative Colitis
NCT05507931 ·Status: COMPLETED ·Phase: NA
-
Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis
NCT06998277 ·Status: COMPLETED ·Phase: NA
-
The Diagnostic Value of Serum Oncostatin M and Galactin 3 as Biomarkers in Diagnosis of Ulcerative Colitis Disease
NCT06959654 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06290934 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effects of Carrageenan-Elimination Diet on Ulcerative Colitis Disease Activity
NCT01065571 ·Status: COMPLETED ·Phase: NA
-
Anthocyanin Rich Extract (ACRE) in Patients With Ulcerative Colitis
NCT04000139 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Prebiotics in Ulcerative Colitis
NCT06495658 ·Status: RECRUITING ·Phase: NA
-
Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis
NCT05761327 ·Status: COMPLETED ·Phase: NA
-
Curcumin for Prevention of Relapse in Patients With Ulcerative Colitis
NCT03122613 ·Status: TERMINATED ·Phase: NA
-
Wild Blueberries in Colitis
NCT06698601 ·Status: RECRUITING ·Phase: NA
-
Fermented Food-Supplemented Diet in Ulcerative Colitis
NCT04401605 ·Status: RECRUITING ·Phase: NA
-
A Clinical Study to Assess the Effects of KB295 in Patients With Ulcerative Colitis (UC) on Gut Microbiota Structure and Function
NCT04508413 ·Status: COMPLETED ·Phase: NA
-
Diet Study on Ulcerative Colitis
NCT04147598 ·Status: COMPLETED ·Phase: NA
-
Pilot Study of Green Tea Extract (Polyphenon E®)in Ulcerative Colitis
NCT00718094 ·Status: COMPLETED ·Phase: PHASE2
-
Bio-enhanced Curcumin as an Add-on Treatment in Maintaining Remission of Ulcerative Colitis
NCT02683759 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Probiotic Supplementation on the Immune System in Patients With Ulcerative Colitis in Amman, Jordan
NCT04223479 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Prebiotics in Reducing Inflammation and Clinical Endpoints in Ulcerative Colitis (PRInCE-UC)
NCT06050811 ·Status: COMPLETED ·Phase: NA
-
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04033445 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease)
NCT01765998 ·Status: UNKNOWN ·Phase: PHASE4
-
Quality of Life in Pediatric Inflammatory Bowel Disease
NCT00061737 ·Status: COMPLETED
-
Fecal Microbiota Therapy Vs 5-aminosalicylates for Induction of Remission in Newly Diagnosed Mild-moderately Active UC
NCT03716388 ·Status: UNKNOWN ·Phase: PHASE3
-
Bio-enhanced Curcumin as an Add-On Treatment in Mild to Moderate Ulcerative Colitis
NCT02683733 ·Status: UNKNOWN ·Phase: PHASE3