Valbenazine in Obsessive Compulsive Disorder
NCT07111988 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-05-04
Summary
The primary aim of the study is to examine the efficacy and safety of valbenazine in adults with moderate to severe obsessive-compulsive disorder (OCD).
Conditions
- Obsessive-Compulsive Disorder
Interventions
- DRUG
-
Valbenazine
Selective vesicular monoamine transporter 2 (VMAT2) inhibitor
- DRUG
-
Pill that contains no medicine
Sponsors & Collaborators
-
Neurocrine Biosciences
collaborator INDUSTRY -
University of Chicago
lead OTHER
Principal Investigators
-
Jon E Grant, MD, JD, MPH · University of Chicago
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-31
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
- FDA Drug
- Yes
More Related Trials
-
A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder
NCT00126282 ·Status: COMPLETED ·Phase: NA
-
Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)
NCT00728923 ·Status: COMPLETED ·Phase: PHASE2
-
Cannabinoid Medication for Adults With OCD
NCT02911324 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder
NCT01371110 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
NCT03356483 ·Status: COMPLETED ·Phase: PHASE1
-
Personalized Computerized Inhibitory Control Training for OCD
NCT02378896 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder
NCT04693351 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)
NCT01100255 ·Status: COMPLETED ·Phase: PHASE2
-
Examining the Usage of Dopamine Blockers in OCD Patients
NCT00496925 ·Status: COMPLETED
-
Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder
NCT04708834 ·Status: TERMINATED ·Phase: PHASE3
-
Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder
NCT01368510 ·Status: COMPLETED ·Phase: NA
-
Trial of Low-Dose Xenon For The Treatment Of Obsessive-Compulsive Disorder
NCT02098148 ·Status: WITHDRAWN ·Phase: PHASE2
-
Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)
NCT02062658 ·Status: COMPLETED ·Phase: PHASE2
-
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
NCT01687140 ·Status: UNKNOWN ·Phase: PHASE2
-
Effects of Repeated Psilocybin Dosing in OCD
NCT05370911 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)
NCT00464698 ·Status: COMPLETED ·Phase: PHASE4
-
Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder
NCT00956085 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine Infusion for Obsessive-Compulsive Disorder
NCT01349231 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
NCT04641143 ·Status: COMPLETED ·Phase: PHASE3
-
Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder
NCT03299166 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Mindfulness-Based Cognitive Therapy in a Clinical Sample of OCD Patients
NCT02217995 ·Status: COMPLETED ·Phase: NA
-
St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.
NCT00035438 ·Status: COMPLETED ·Phase: PHASE2
-
Multimodal Assessment of Cannabinoid Target Engagement in Adults With Obsessive-Compulsive Disorder
NCT04880278 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD
NCT00371176 ·Status: COMPLETED ·Phase: NA
-
The Study of the Pathogenesis and Cognitive Behavioral Group Therapy in Obsessive-Compulsive Disorder
NCT02739061 ·Status: COMPLETED ·Phase: NA