Study Evaluating the Effect of Humiome® Post LB on Stress, Anxiety, and Cognition in Aging Adults
NCT07110896 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 236
Last updated 2026-03-11
Summary
To assess the effect of 3 months of daily consumption of a postbiotic (inactivated lactic acid bacteria) Humiome® Post LB on stress measured by the Depression Anxiety Stress Scale-21 (DASS-21) adjusted on baseline in study participants when compared to placebo
Conditions
- Healthy Aging
Interventions
- DIETARY_SUPPLEMENT
-
Humiome Post LB (Postbiotic)
Heat-inactivated lactobacilli with fermented medium (a postbiotic) in 340mg powder format
- DIETARY_SUPPLEMENT
-
Placebo
Microcrystalline cellulose, 340mg powder format
Sponsors & Collaborators
-
Analyze & Realize
collaborator NETWORK -
dsm-firmenich Switzerland AG
lead INDUSTRY
Principal Investigators
-
Mehdi Sadaghian, PhD · dsm-firmenich Switzerland AG
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-08-01
- Primary Completion
- 2026-10-31
- Completion
- 2026-11-30
Countries
- France
- Germany
Study Locations
More Related Trials
-
Post-biotic Intervention for Acute Stress Management
NCT06097182 ·Status: COMPLETED ·Phase: NA
-
The Effect of Probiotic Supplementation on Mental Health in Healthy Volunteers
NCT06391216 ·Status: COMPLETED ·Phase: NA
-
A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress
NCT04125810 ·Status: COMPLETED ·Phase: PHASE2
-
Probiotics, Brain Structure and Psychological Variables
NCT03478527 ·Status: COMPLETED ·Phase: NA
-
Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress
NCT05392556 ·Status: COMPLETED ·Phase: NA
-
Effectiveness and Safety of Probiotics in Relieving Anxiety and Depression
NCT06629441 ·Status: COMPLETED ·Phase: NA
-
Evaluation of a Probiotic On Anxiety and Stress in Healthy Adults Sensible to Daily Stress
NCT00807157 ·Status: COMPLETED ·Phase: NA
-
Probiotic Intervention for Stress and Cognition
NCT04931082 ·Status: COMPLETED ·Phase: NA
-
Psychophysiological Effects of Probiotic Supplementation
NCT05226520 ·Status: COMPLETED ·Phase: NA
-
Acute and Chronic Effects of Ecologic Barrier© on Mood and Cognition
NCT04951687 ·Status: COMPLETED ·Phase: NA
-
The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation and Oxidative Stress Parameters and Faecal Microbiota in Patients With Depression Depending on Metabolic Syndrome Comorbidity
NCT04756544 ·Status: UNKNOWN ·Phase: PHASE3
-
The Efficacy of a Probiotic Blend on Stress in Moderately Stressed Teens
NCT05766306 ·Status: COMPLETED ·Phase: PHASE2
-
Probiotics on Sleep Among Adults Study
NCT04767997 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety
NCT07058324 ·Status: RECRUITING ·Phase: NA
-
Effect of Two Probiotic Formulations on Mental Health and Mood Biomarkers in Adults With Depressive Symptoms
NCT05564767 ·Status: COMPLETED ·Phase: NA
-
The Impact of Probiotics on Well-being in Women
NCT06507111 ·Status: COMPLETED ·Phase: NA
-
Evaluating the Potential of Probiotic Supplementation Sleep Quality
NCT06486064 ·Status: COMPLETED ·Phase: NA
-
Effect of 4-week Oral Administration of a Fermented Dairy Product Containing Lactobacillus Rhamnosus CNCM I-3690, on Subjective State Anxiety Levels in Healthy Women Undergoing Academic Stress.
NCT04780763 ·Status: COMPLETED ·Phase: NA
-
Investigating the Effectiveness of 2 Different Doses of BIOHM FX Probiotic Blend in Improving Digestive Symptoms
NCT06782945 ·Status: ACTIVE_NOT_RECRUITING
-
Probiotics and Examination-related Stress in Healthy Medical Students
NCT03427515 ·Status: COMPLETED ·Phase: NA
-
Probiotic Intervention for Acute Stress
NCT03284905 ·Status: COMPLETED ·Phase: NA
-
Effect of a Fermented Dairy Food With Probiotics on Mental Performance
NCT05323825 ·Status: COMPLETED ·Phase: NA
-
Probiotics for Anxiety Study
NCT06466603 ·Status: ACTIVE_NOT_RECRUITING
-
Effect of Probiotics on Stress in Young Adults
NCT05840978 ·Status: COMPLETED ·Phase: NA
-
Study on the Effects of a Probiotic on Autonomic and Psychological Stress
NCT02417454 ·Status: COMPLETED ·Phase: PHASE3