MedTrace Logo

Probiotics and Examination-related Stress in Healthy Medical Students

NCT03427515 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2018-02-09

No results posted yet for this study

Summary

Probiotics are live microorganisms exhibiting multiple properties beneficial to health. An increasing body of evidence indicates that probiotics may support healthy brain function and may relieve stress. Recent research in this area has examined lactic acid bacteria in detail, but little is known about the stress-relieving effects of Saccharomyces, a yeast with probiotic properties.

Psychological stress is a factor that allows people to successfully cope with various daily life situations. On the other hand, excessive stress may lead to bodily harm and decrease performance, e.g. academic achievements. Probiotics may help manage stress, but little is known whether probiotics improve performance under stress.

The aim of this trial is to examine whether the healthy medical students may demonstrate better performance in academic examinations when supplementing their diet with a yeast probiotic strain Saccharomyces boulardii (CNCM I-1079) or bacterial probiotic strain Lactobacillus rhamnosus GG (ATCC 53103). The secondary aim of the trial is to evaluate the potential effects of this supplementation on state anxiety as well as on biochemical and physiological stress markers.

Conditions

  • Healthy
  • Stress-related Problem
  • Anxiety

Interventions

DIETARY_SUPPLEMENT

Lactobacillus rhamnosus GG (ATCC 53103)

30 days of supplementation, 6x10\^9 CFU/day

DIETARY_SUPPLEMENT

Saccharomyces boulardii (CNCM I-1079)

30 days of supplementation, 5x10\^9 CFU/day

DIETARY_SUPPLEMENT

Placebo

30 days of supplementation

Sponsors & Collaborators

  • Medical University of Lodz

    lead OTHER

Principal Investigators

  • Michał S. Karbownik, PhD · Medical University of Lodz

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-20
Primary Completion
2016-06-20
Completion
2016-06-20

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03427515 on ClinicalTrials.gov