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HIIT Versus MICT in COPD: Effects on Oxygenation, Pulmonary Function, and Strength

NCT07109687 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-08-07

No results posted yet for this study

Summary

Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition marked by airflow limitation and chronic inflammation, leading to reduced exercise capacity, peripheral muscle dysfunction, and dyspnea. High-Intensity Interval Training (HIIT) may offer a promising alternative for patients with low exercise tolerance; however, evidence on its effectiveness remains limited.

This study aims to compare the effects of HIIT and Moderate-Intensity Continuous Training (MICT) on muscle oxygenation, pulmonary function, exercise capacity, and peripheral muscle strength in individuals with COPD. Participants will undergo an 8-week exercise program, twice weekly. HIIT will consist of 1-minute intervals at 90% and 30-40% of peak workload, while MICT will involve continuous cycling at 65% of peak workload. Outcomes will be assessed at baseline, week 4, and week 8. Data will be analyzed using SPSS. This study seeks to determine the more effective training modality to optimize COPD rehabilitation.

Conditions

  • Chronic Obstructive Pulmonary Disease (COPD)

Interventions

OTHER

HIIT GROUP

Participants will perform a 31-minute protocol on a cycle ergometer consisting of 1-minute high-intensity intervals at 90% of peak workload (W peak) and low-intensity intervals at 30-40% of W peak, twice a week for 8 weeks.

OTHER

MICT

Moderate intensity continous exercise

Sponsors & Collaborators

  • Antalya Bilim University

    collaborator OTHER

  • Hacettepe University

    collaborator OTHER

  • Aynur Demirel

    lead OTHER

Principal Investigators

  • Fulsen Bozkus, MD., Prof. · Sağlık Bilimleri University Antalya Health Application and Research Center

  • Aynur Demirel, PT, PhD, Assoc. Prof. · Hacettepe University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2027-03-01
Completion
2027-06-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07109687 on ClinicalTrials.gov