Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA)

Summary

PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.

Conditions

• Chronic Pancreatitis
• Surgery
• Minimally Invasive Surgical Technique
• Robot Surgica
• Robot Surgery
• Minimally Invasive Surgery
• Pancreaticojunostomy

Interventions

PROCEDURE

Robot-assisted lateral pancreaticojejunostomy

Robot-assisted

PROCEDURE

Open lateral pancreaticojejunostomy

Open surgery

Sponsors & Collaborators

• St. Antonius Hospital

  collaborator OTHER

• Erasmus Medical Center

  collaborator OTHER

• Maastricht University Medical Center

  collaborator OTHER

• Universitätsklinikum Hamburg-Eppendorf

  collaborator OTHER

• University Medical Center Groningen

  collaborator OTHER

• Onze Lieve Vrouwe Gasthuis

  collaborator OTHER

• Catharina Ziekenhuis Eindhoven

  collaborator OTHER

• Radboud University Medical Center

  collaborator OTHER

• Medisch Spectrum Twente

  collaborator OTHER

• Leiden University Medical Center

  collaborator OTHER

• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

  lead OTHER

Principal Investigators

• M.G. Besselink, Amsterdam UMC · prof. dr.

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-04-16

Primary Completion

2026-12-31

Completion

2026-12-31

Countries

• Netherlands

Study Locations