Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World
NCT07105631 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-08-06
Summary
The Chidamide + sintilimab ± bevacizumab regimen has become a post-treatment option for clinicians and patients after being included in the guidelines. The CAPability-01 study is a phase II RCT, with a limited number of enrolled subjects. Further observation of the safety and clinical real-world application status of the sidibemab combination regimen is needed in a larger sample size prospective observational cohort study. The primary endpoint of this study is the safety events of the sidibemab combination regimen.
Conditions
Sponsors & Collaborators
-
West China Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-10
- Primary Completion
- 2026-07-30
- Completion
- 2027-07-30
Countries
- China
Study Locations
More Related Trials
-
Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer
NCT07154316 ·Status: RECRUITING ·Phase: PHASE2
-
Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer
NCT06764680 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer
NCT05215379 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Combined Use of Raltitrexed and S-1 as Treatment for Patients With Metastasizing Colorectal Cancer
NCT02618356 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Outcomes of Treatment With Immunomodulator Plus Cancer Therapies for Patients With Colorectal Cancer
NCT06557668 ·Status: RECRUITING
-
Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer
NCT05671809 ·Status: NOT_YET_RECRUITING
-
Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer
NCT06698757 ·Status: RECRUITING ·Phase: PHASE2
-
Maintenance Chemotherapy for Metastatic Colorectal Carcinoma and Biological Marker
NCT02043821 ·Status: UNKNOWN ·Phase: NA
-
Neoantigen-based Peptide Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment
NCT06751914 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Combination Immunotherapy in Patients With Metastatic Colorectal Cancer
NCT05414461 ·Status: COMPLETED ·Phase: PHASE2
-
Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal Cancer
NCT05635149 ·Status: UNKNOWN
-
Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer
NCT06931808 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE4
-
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
NCT07319364 ·Status: RECRUITING ·Phase: PHASE1
-
Metronomic Versus Conventional Chemotherapy in as Maintenance Treatment in mCRC
NCT02893540 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer
NCT07297030 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Trial of Using SIB-IMRT in Preoperative Radiotherapy for Locally Advanced Rectum Cancer
NCT02195141 ·Status: UNKNOWN ·Phase: PHASE2
-
Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer
NCT03532711 ·Status: COMPLETED
-
Low-dose Capecitabine Adjuvant Chemotherapy for Elderly Patients With Stage II/III Colorectal Cancer
NCT02316535 ·Status: UNKNOWN ·Phase: PHASE3
-
SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.
NCT06835179 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
The Real Clinical Background of Advanced Colorectal Cancer Treatment Situation Survey
NCT01549067 ·Status: UNKNOWN
-
Study of Postoperative Concurrent Chemo-radiation With Capecitabine in Elderly Rectal Cancer Patients
NCT01268943 ·Status: COMPLETED ·Phase: PHASE1
-
Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors
NCT06806046 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Neoantigen-based Peptide Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment
NCT06751966 ·Status: RECRUITING ·Phase: NA
-
Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer (CASTLE-08)
NCT05781074 ·Status: RECRUITING ·Phase: PHASE2
-
Tirellizumab+Anlotinib VS Anlotinib for MSS-type CRC
NCT06573424 ·Status: COMPLETED