A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer
NCT06682247 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-11-12
Summary
This is an observational , multicenter, real-world study aimed at evaluating the efficacy and safety of the combination of immune checkpoint inhibitors, chidamide and antiangiogenic agents in Microsatellite Stable advanced colorectal cancer patients.
Conditions
- Colorectal Cancer Metastatic
Interventions
- DRUG
-
Chidamide, Tucidinostat; PD-1/PD-L1 inhibitor or double antibodies; Bevacizumab or tyrosine kinase inhibitors
Chidamide, Tucidinostat; PD-1/PD-L1 inhibitor or double antibodies; Bevacizumab or tyrosine kinase inhibitors
Sponsors & Collaborators
-
Feng Wang
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-15
- Primary Completion
- 2025-06-15
- Completion
- 2025-12-31
More Related Trials
-
PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer
NCT04301557 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer
NCT04411524 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer-
NCT06895577 ·Status: WITHDRAWN ·Phase: PHASE2
-
Gut Microbiota Reconstruction for NSCLC Immunotherapy
NCT05008861 ·Status: UNKNOWN ·Phase: PHASE1
-
Comparing 68Ga-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis
NCT07079462 ·Status: RECRUITING ·Phase: PHASE2
-
Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer
NCT06521866 ·Status: RECRUITING ·Phase: PHASE2
-
High-activity Natural Killer Immunotherapy for Small Metastases of Colorectal Cancer
NCT03008499 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer
NCT05914389 ·Status: RECRUITING ·Phase: PHASE2
-
Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer
NCT01080547 ·Status: COMPLETED ·Phase: PHASE3
-
Tirellizumab+Anlotinib VS Anlotinib for MSS-type CRC
NCT06573424 ·Status: COMPLETED
-
Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer
NCT06764680 ·Status: RECRUITING ·Phase: PHASE2
-
Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer
NCT05972655 ·Status: RECRUITING ·Phase: PHASE2
-
Involve-site Radiotherapy Combined With Chemotherapy and Immunotherapy as Neoadjuvant Treatment for Locally Advanced Rectal Cancer
NCT07161115 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody
NCT06014944 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
FMT+Immunotherapy+Chemotherapy As First-line Treatment for Driver-gene Negative Advanced NSCLC
NCT06403111 ·Status: RECRUITING ·Phase: PHASE2
-
Exploratory Clinical Study of Claudin18.2-Targeted CAR-DC and CAR-T Therapy in Advanced Colorectal Cancer
NCT06946615 ·Status: RECRUITING ·Phase: PHASE1
-
Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer
NCT06204094 ·Status: RECRUITING ·Phase: PHASE2
-
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
NCT07319364 ·Status: RECRUITING ·Phase: PHASE1
-
Camrelizumab Combined With Trastuzumab and Chemotherapy in Patients With HER2-positive Advanced Colorectal Cancer
NCT05193292 ·Status: UNKNOWN ·Phase: PHASE2
-
Total Neoadjuvant Therapy With PD-1 for Locally Advcancer Rectal Cancer
NCT07214142 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
NCT06239870 ·Status: RECRUITING ·Phase: PHASE2
-
The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer
NCT05555888 ·Status: RECRUITING ·Phase: PHASE2
-
Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer
NCT03532711 ·Status: COMPLETED
-
Safety Study of Capecitabine With Radiation in Elderly Rectal Cancer
NCT01584544 ·Status: COMPLETED ·Phase: PHASE1
-
Detection and Enumeration of Circulating Tumor Cells in Rectal Cancer
NCT01671891 ·Status: UNKNOWN