The Effect of Oral Oxytocin and Atosiban on Social Attention
NCT07093060 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2025-07-30
Summary
The main aim of the present study is to investigate whether orally (lingual spray) administered oxytocin influences human social attention and behaviors via oxytocin receptors and whether its effects are dose- and task-dependent.
Conditions
- Healhty
Interventions
- DRUG
-
Oxytocin lower dose (24IU)
Oxytocin (24IU) will be administered as a lingual spray (6, 0.1 puffs (4IU per puff) of spray on and under the tongue)
- DRUG
-
Oxytocin higher dose (48IU)
48IU oxytocin administered as a lingual spray (6, 0.1ml sprays (8IU per puff) on or under the tongue)
- DRUG
-
Atosiban
150ug atosiban administered by lingual sprays (6, 0.1ml sprays on and under the tongue)
- DRUG
-
Placebo administered as a lingual spray (6, 0.1 ml sprays one and under the tongue. Placebo has the same composition of 0.9% saline and glycerol as for oxytocin and atosiban interventions
Sponsors & Collaborators
-
University of Electronic Science and Technology of China
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-06-09
- Primary Completion
- 2025-11-30
- Completion
- 2025-11-30
Countries
- China
Study Locations
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