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Neural Correlates of Empathogenic and Affiliative Actions of Oxytocin

NCT01701180 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2014-12-03

No results posted yet for this study

Summary

Mounting evidence indicates that the intranasal administration of the neuropeptide oxytocin has prosocial effects. However, the neural substrates of these effects are still unclear. The investigators hypothesized that a single dose administration of oxytocin should increase empathogenic and affiliative responses and that these effects are mediated by an increased insula activity.

Conditions

  • Healthy

Interventions

DRUG

Oxytocin

24 IU; 3 puffs per nostril, each with 4 IU OXT

DRUG

Placebo

Sponsors & Collaborators

  • University Hospital, Bonn

    lead OTHER

Principal Investigators

  • René Hurlemann, MD PhD M.Sc. · Department of Psychiatry University of Bonn

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2013-08-31
Completion
2013-08-31

Countries

  • Germany

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01701180 on ClinicalTrials.gov