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The Influence of Oxytocin on Socio-communicative Sensitivity

NCT03096249 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2022-07-22

No results posted yet for this study

Summary

Oxytocin (OT) is a neuropeptide that acts as a neurotransmitter and neuromodulator in the brain. Previous studies have shown that intranasal administration of OT improves social cognition and behavior (e.g. emotion recognition). In the current study, we want to gain more insight into the underlying mechanisms by which OT influences emotion recognition. More specifically, we will investigate whether intranasal administration of OT enhances the salience of social (compared to non-social) information and whether it increases the neural sensitivity for subtle socio-emotional cues, by recording scalp electroencephalography (EEG) during Fast Periodic Visual Stimulation (FPVS).

Conditions

  • Oxytocin

Interventions

DRUG

Oxytocin

Syntocinon nasal spray: single dose of 24IU (3 puffs of 4IU per nostril)

OTHER

Placebo

Placebo spray: single dose (3 puffs per nostril).

Sponsors & Collaborators

  • KU Leuven

    lead OTHER

Principal Investigators

  • Kaat Alaerts, Professor · KU Leuven (Catholic University Leuven)

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-21
Primary Completion
2017-05-30
Completion
2017-07-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03096249 on ClinicalTrials.gov