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Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter

NCT07085949 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2026-02-24

No results posted yet for this study

Summary

The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.

Conditions

  • Optic Nerve Sheath Diameter

Interventions

OTHER

5 cmH2O PEEP

5 cmH2O PEEP will be administered during mechanical ventilation

OTHER

10 cmH2O PEEP

10 cmH2O PEEP will be administered during mechanical ventilation

Sponsors & Collaborators

  • Izmir City Hospital

    lead OTHER_GOV

Principal Investigators

  • Zeki Tuncel Tekgül, Professor · Izmir City Hospital

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-30
Primary Completion
2026-01-01
Completion
2026-01-02

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07085949 on ClinicalTrials.gov