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Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain

NCT07080788 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-03-02

No results posted yet for this study

Summary

The goal of this pilot study is to assess whether 4-weeks of verified smoking abstinence following financial incentive treatment for smoking cessation improves physiological markers of chronic pain risk in adult Native American smokers.

The main aims to answer are:

1. Determine study feasibility.
2. Obtain effect sizes for changes in pain amplification and pain inhibition in abstinent vs non-abstinent Native Americans.
3. Obtain effect sizes for variables in the conceptual model of the Native American smoking-pain relationship.

Conditions

  • Smoking Cessation Intervention
  • Pain
  • Smoking (Tobacco) Addiction

Interventions

BEHAVIORAL

Smoking Cessation

Investigators will provide financial incentives for biochemically verified abstinence at 4 weeks following treatment. This incentive is consistent with recent research using macro-level financial incentives and incorporates both short-term and long-term incentives to shape behavior.

Sponsors & Collaborators

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Jamie L Rhudy, PhD · University of Oklahoma Health Sciences

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-01
Primary Completion
2027-06-30
Completion
2028-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07080788 on ClinicalTrials.gov