Prostate Cancer Vaccines
NCT07068555 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2025-07-20
Summary
Tumor antigens are protein fragments produced by cancer cells carrying genetic mutations, and many tumor antigens are similar to normal protein antigens, making them unrecognizable by the immune system. Many tumor vaccines are prepared based on a single tumor antigen. This study is based on multiple target antigens using tumor lysates or synthetic peptides. The immune modulation by dendritic-cell (DC)-based cancer vaccines consists of genetically modified DCs to activate T cells to target cancer cells. The study is based on an advanced cancer vaccine technology, which aims to evaluate the safety and potential benefit of the novel immunomodulatory prostate cancer DC vaccines.
Conditions
- Prostate Cancer Indications
Interventions
- BIOLOGICAL
-
Immunomodulatory DC vaccines to target prostate cancer
1 to 2 injections, with an interval of one month, of 1\~2x10\^7 DC vaccine administered subcutaneously
Sponsors & Collaborators
-
Shenzhen Geno-Immune Medical Institute
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-15
- Primary Completion
- 2028-06-15
- Completion
- 2028-12-15
Countries
- China
Study Locations
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