Vaccine Therapy in Treating Patients With Kidney Cancer
NCT00096629 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2018-04-25
Summary
RATIONALE: Vaccines made from DNA may make the body build an immune response to kill tumor cells.
PURPOSE: This randomized phase I trial is studying the side effects and best dose of vaccine therapy in treating patients with kidney cancer.
Conditions
Interventions
- BIOLOGICAL
-
human prostate-specific membrane antigen plasmid DNA vaccine
- BIOLOGICAL
-
mouse prostate-specific membrane antigen plasmid DNA vaccine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Susan Slovin, MD, PhD · Memorial Sloan Kettering Cancer Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-11-30
- Primary Completion
- 2018-04-30
- Completion
- 2018-04-30
Countries
- United States
Study Locations
More Related Trials
-
RNA-Loaded Dendritic Cell Cancer Vaccine
NCT00087984 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating Patients With Renal Cell Carcinoma
NCT00862303 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Autologous Dendritic Cells in Treating Patients With Metastatic Kidney Cancer
NCT01826877 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccination of Patients With Renal Cell Cancer With Dendritic Cell Tumor Fusions and GM-CSF
NCT00458536 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer
NCT00823524 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccine Combined With CIK Cells in Patients With Renal Cell Carcinoma
NCT01924156 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Safety/Efficacy of a Vaccine Prepared From Dendritic Cells Combined With Tumor Cells to Treat Advanced Kidney Cancer
NCT00050323 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors
NCT06509490 ·Status: RECRUITING ·Phase: NA
-
Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
NCT00923390 ·Status: TERMINATED ·Phase: PHASE1
-
Tumor RNA Transfected Dendritic Cell Vaccines
NCT00108264 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Finding Study of a DNA Vaccine Delivered With Intradermal Electroporation in Patients With Prostate Cancer
NCT00859729 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
NK Cells Infusion for Advanced Malignancies
NCT03619954 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Effectiveness of a Vaccine for Prostate Cancer That Uses Each Patients' Own Immune Cells.
NCT00289341 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating
NCT02487550 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma
NCT00625755 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dendritic Cell Vaccination for Patients with Solid Tumors
NCT01291420 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Prostate Cancer Vaccines
NCT07068555 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Refractory Stage IV Cancer
NCT00057915 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer
NCT00909558 ·Status: SUSPENDED ·Phase: PHASE1
-
A Pilot Study of Vaccination With Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer
NCT00972309 ·Status: COMPLETED ·Phase: PHASE1
-
NKG2D-CAR-NK92 Cells Immunotherapy for Solid Tumors
NCT05528341 ·Status: RECRUITING ·Phase: PHASE1
-
Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139
NCT02362464 ·Status: COMPLETED ·Phase: PHASE2
-
Engineered Immune Effectors Against Cervical Cancer
NCT03362619 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Autologous Dendritic Cell Vaccine in Kidney Cancer
NCT05127824 ·Status: RECRUITING ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Non-Small Cell Lung Cancer
NCT00023985 ·Status: COMPLETED ·Phase: PHASE1