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Lifestyle, Fitness, and Plasma Biomarkers in Healthy Young Adults

NCT07032168 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 31

Last updated 2026-03-09

No results posted yet for this study

Summary

Lifestyle play a key role in modulating brain health by directly influencing a number of key biological processes, such as neuroplasticity, neurogenesis, and regulation of biomarkers associated with cognitive decline. Factors such as physical activity, diet, sleep quality, stress management, and body composition have been shown to have a significant impact on neuroprotection and cognitive performance. These factors not only contribute to maintaining metabolic and functional balance in the body, but are also linked to the expression of biomarkers such as brain-derived neurotrophic factor (BDNF) and Tau protein phosphorylated at the amino acid threonine 217 (PTau217), which are essential for the maintenance of neuronal health and the prevention of neurodegenerative diseases. In this sense, a healthy lifestyle, characterized by regular physical activity, a balanced diet, good quality sleep, low stress levels and adequate body composition, can act as a protective factor against cognitive decline from early stages of life.

Conditions

  • Healthy Young Adults

Sponsors & Collaborators

  • European University Miguel de Cervantes

    lead OTHER

Principal Investigators

  • Simone Lista, PhD · Miguel de Cervantes European University

  • Susana López-Ortiz, PhD · Miguel de Cervantes European University

Eligibility

Min Age
18 Years
Max Age
24 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-16
Primary Completion
2025-10-31
Completion
2025-10-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07032168 on ClinicalTrials.gov