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Role of Manuka Honey in Lowering Pain and Boosting Healing After Gum Graft Surgery.

NCT07016373 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2025-06-11

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if medical grade Manuka Honey works to lower pain and improve healing sites after gum grafting surgery. The main questions are:

* Does medical grade Manuka honey lower pain and painkiller use after gum grafting surgery ?
* Does medical grade Manuka honey boost healing after gum grafting surgery ?

Researchers will compare, within the same patient, the results of a surgery with the application of Manuka honey in a retainer to a surgery without the application of honey in the retainer for the healing period.

Participants will:

* Visit the clinic for their first surgery.
* Fill up a daily survey to explain their level of pain and the amount of painkiller drugs used.
* Visit the clinic once every week for 6 weeks for follow-ups.
* Visit the clinic for their second surgery, four weeks after the first one.
* Fill up a daily survey to explain their level of pain and the amount of painkiller drugs used after the second surgery.
* Visit the clinic once every week for 6 weeks for follow-ups on the second surgery
* Fill a survey to compare both surgeries .
* Visit the clinic 2 months, 6 months and one year after the surgeries for more follow-ups.

Conditions

  • Gingival Recession, Mucogingival Surgery

Interventions

DEVICE

Palatal Plate without Manuka Honey

A Palatal plate without Manuka Honey will be inserted by a blinded investigator on the donor site for post-operative procedures.

DEVICE

Palatal plate with Manuka Honey

A Palatal plate with Manuka Honey will be inserted by a blinded researcher on the donor site.

Sponsors & Collaborators

  • Nancy Mouradian

    lead OTHER

Principal Investigators

  • Nancy Mouradian, DMD, MSc, FRCD(C), Dip.ABP · Laval University

  • Benjamin Labelle, DMD, MSc, Cert. Perio, FRCD(C)

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-20
Primary Completion
2026-12-26
Completion
2027-01-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07016373 on ClinicalTrials.gov