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Comparative Effects of CGF and PRP in Impacted Third Molar Surgery

NCT07320170 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2026-01-08

No results posted yet for this study

Summary

This study evaluates the effects of two different blood products obtained from the patient's own blood (Concentrated Growth Factor \[CGF\] and Platelet-Rich Plasma \[PRP\]) on healing after wisdom tooth extraction. The aim is to determine whether applying these materials to the extraction area reduces postoperative pain, facial swelling, and the risk of dry socket compared to standard healing.

Conditions

  • Impacted Third Molar

Interventions

BIOLOGICAL

Concentrated Growth Factor (CGF)

Standard surgical extraction followed by the placement of a Concentrated Growth Factor (CGF) clot into the extraction socket immediately after tooth removal.

BIOLOGICAL

Platelet-Rich Plasma (PRP)

Standard surgical extraction followed by submucosal injection of Platelet-Rich Plasma (PRP) around the extraction site.

Sponsors & Collaborators

  • Recep Tayyip Erdogan University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-02
Primary Completion
2025-05-02
Completion
2025-05-02

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07320170 on ClinicalTrials.gov