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Neural Substrates Underlying Adaptations in Manual Dexterity of Older Adults

NCT07011160 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2025-06-08

No results posted yet for this study

Summary

Age-related declines in motor function can compromise independence and quality of life. This project examines how practice and somatosensory stimulation reshape the neural control of hand muscles in older adults, leveraging neuroplasticity to enhance dexterity. By identifying modifiable neural mechanisms that underlie improved motor performance, this research lays the groundwork for targeted, non-invasive interventions that can be translated into clinical and community settings to support healthy aging and functional independence.

Conditions

  • Aging Hands

Interventions

BEHAVIORAL

Transcutaneous electrical nerve stimulation (TENS)

Force-steadiness training will be performance either without (sham) or paired with TENS.

BEHAVIORAL

Familiarization

Participants will perform 25 trials of the Grooved Pegboard Test

Sponsors & Collaborators

  • University of Colorado, Boulder

    lead OTHER

Principal Investigators

  • Roger M Enoka, PhD · University of Colorado, Boulder

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
54 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-04-01
Primary Completion
2030-03-30
Completion
2030-03-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07011160 on ClinicalTrials.gov