Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis
NCT06993454 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2026-04-17
Summary
The overall aim of this study is to investigate the effects of exercise on the amount of glucose that is made by the liver in people with and without Type 2 diabetes (T2D) and hepatic steatosis (fatty liver).
Conditions
- Type 2 Diabetes
- Hepatic Steatosis
Interventions
- OTHER
-
Magnetic Resonance Liver Assessment
Liver fat will be measured by MR imaging to assess level of hepatic steatosis.
- OTHER
-
Bike Exercise VO2max
Maximal fitness measured by cycle ergometer.
- OTHER
-
DEXA
Measure body composition (fat and lean body mass).
Sponsors & Collaborators
-
AdventHealth Translational Research Institute
lead OTHER
Principal Investigators
-
Justine Mucinski, PhD · AdventHealth
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-25
- Primary Completion
- 2026-04-30
- Completion
- 2026-04-30
Countries
- United States
Study Locations
More Related Trials
-
Effect of Training Intensity on Health Outcomes in Diabetes
NCT03349944 ·Status: COMPLETED ·Phase: NA
-
Exercise Resistance in Type 2 Diabetes
NCT01911104 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Effects of High-Intensity Interval Training Exercise in Adolescents With Hepatosteatosis
NCT04342390 ·Status: COMPLETED ·Phase: NA
-
Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes
NCT00739180 ·Status: COMPLETED ·Phase: NA
-
Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes
NCT01883258 ·Status: COMPLETED ·Phase: NA
-
Effect of Exercise on Insulin Resistance
NCT01941277 ·Status: TERMINATED ·Phase: NA
-
Basic Research Study to Examine the Relation Between Muscle Insulin Resistance and Lipid Production in the Liver.
NCT02196051 ·Status: COMPLETED ·Phase: NA
-
Restoring 24-hour Substrate Rhythmicity to Improve Glycemic Control by Timing of Lifestyle Factors
NCT05123963 ·Status: RECRUITING ·Phase: NA
-
Effect of Exercise on Cardiometabolic Risk Factors in Type II Diabetic Patients
NCT04759469 ·Status: COMPLETED ·Phase: NA
-
Blood Flow Responses to an Oral Glucose Tolerance Test in Type 2 Diabetes
NCT00972452 ·Status: COMPLETED ·Phase: NA
-
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans
NCT00710008 ·Status: COMPLETED ·Phase: NA
-
The Effects of Altering Physical Activity on Cardiometabolic Health
NCT01879059 ·Status: COMPLETED ·Phase: NA
-
Mitochondrial Metabolism and Oxidative Stress in Function of the Physical Exercise and Nutritional Counseling in T2DM
NCT07251504 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls
NCT01765894 ·Status: COMPLETED
-
The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients
NCT00472342 ·Status: UNKNOWN ·Phase: NA
-
Training Effects on Fuel Metabolism
NCT02150889 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes
NCT03500016 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Educational Nutrition and Exercise on the Regulation of Appetite Through Exosomes in Type 2 Diabetics
NCT05259449 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Mechanisms of Fatigability With Diabetes
NCT04442451 ·Status: RECRUITING ·Phase: NA
-
Effect of High-intensity Low-volume Training on Insulin Sensitivity in Type 2 Diabetes
NCT02039934 ·Status: COMPLETED ·Phase: NA
-
Fasted Exercise Training in Type 2 Diabetes
NCT03908281 ·Status: COMPLETED ·Phase: NA
-
Fasted Exercise in People With Type 1 Diabetes
NCT03544684 ·Status: COMPLETED ·Phase: NA
-
Effects of Physical Exercise in Type 2 Diabetics
NCT01095068 ·Status: TERMINATED ·Phase: NA
-
Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes
NCT01323088 ·Status: COMPLETED ·Phase: NA
-
Resistance Training for the Improvement of Glycemic Control in Prediabetes
NCT06697756 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA