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Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Tissues From Egyptian Male Patients and Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Cancer.

NCT06289270 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 38

Last updated 2024-03-01

No results posted yet for this study

Summary

Microbes inhabiting the urinary tract that are playing an important role in maintenance of health and the development of diseases and bladder cancer. There is correlation between initiation of bladder cancer and microbes. Urine and bladder tissues from healthy individuals and patients with bladder cancer were analyzed using 16S rRNA sequencing, results show abundant phylum. Next-generation sequencing technologies will be applied with whole genomic and 16S ribosomal RNA gene sequencing for microbiota profiling in urine and bladder tissue of male healthy individuals and patients with bladder cancer. Results will lead to prevention, diagnosis, and new treatment strategies for bladder cancer.

Conditions

  • Microbiota in Patients With Urinary Bladder Carcinoma in Urine and Cancer Tissues

Sponsors & Collaborators

  • Theodor Bilharz Research Institute

    lead OTHER

Principal Investigators

  • Mohamed M Wishahi, MD · Theodor Bilharz Research Institute

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-09-20
Primary Completion
2026-12-31
Completion
2027-07-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06289270 on ClinicalTrials.gov