Association of Vitamin D Status With Metabolic Markers in Adolescents With Polycystic Ovary Syndrome
NCT06970821 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 106
Last updated 2025-09-18
Summary
This prospective cross-sectional case-control study aims to investigate the relationship between serum vitamin D levels, visceral adipose tissue (VAT) thickness, and metabolic parameters in adolescents diagnosed with polycystic ovary syndrome (PCOS), compared to healthy controls. The study includes 70 adolescents with PCOS and 40 age-matched healthy adolescents, all aged between 12 and 19 years, who attended the adolescent gynecology outpatient clinic of a tertiary care hospital. Serum 25-hydroxy vitamin D \[25(OH)D\] levels, fasting glucose, fasting insulin, lipid profiles, anthropometric measurements, and ultrasound-based VAT thickness were assessed. The study seeks to explore potential associations between vitamin D deficiency and metabolic dysregulation in adolescent PCOS patients and to better understand the early cardiometabolic risks associated with PCOS during adolescence.
Conditions
- Polycystic Ovary Syndrome
- Vitamin D Deficiency
- Insulin Resistance
Sponsors & Collaborators
-
Bagcilar Training and Research Hospital
lead OTHER_GOV
Principal Investigators
-
Nese Hayirlioglu · Bagcilar Training and Research Hospital
Eligibility
- Min Age
- 13 Years
- Max Age
- 19 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-03-01
- Primary Completion
- 2025-05-15
- Completion
- 2025-05-30
Countries
- Turkey (Türkiye)
Study Locations
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