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Metabolic Disturbances in Polycystic Ovary Syndrome (PCOS)

NCT00606671 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 65

Last updated 2008-02-04

No results posted yet for this study

Summary

The scope of the study was to investigate different metabolic aspects that may lead to or are a consequence of insulin resistance in premenopausal women with polycystic ovary syndrome (PCOS). We use gold standard methods for evaluation of insulin resistance. We take muscle and fat biopsies for investigation of gene expression of different cytokines associated with insulin resistance. We investigate the incretin hormones GIP and GLP-1. These two hormones play a central role in glycemic control, and diabetic subjects are known to have alterations in their incretin hormones. The incretin hormones have not previously been investigated in women with PCOS.

Conditions

  • Polycystic Ovary Syndrome

Sponsors & Collaborators

  • Diabetesforeningen

    collaborator OTHER

  • Danish Hospital foundation for medical research. region Copenhagen, The Faroe Islands and Greenland.

    collaborator UNKNOWN

  • Aage Bangs Fond

    collaborator OTHER

  • Hvidovre University Hospital

    lead OTHER

Principal Investigators

  • Pernille Fog Svendsen, MD · Dpt. of Obstetrics and Gynaecology, Copenhagen University Hospital, Hvidovre

Eligibility

Min Age
18 Years
Max Age
38 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2004-02-29
Primary Completion
2006-05-31
Completion
2006-05-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00606671 on ClinicalTrials.gov