Da Qing Offspring Study
NCT06958640 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 5000
Last updated 2025-05-06
Summary
This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups. Based on the original participants, the study will further include their spouses, first to third-generation offspring, and spouses of the offspring. General demographic information will be collected, and anthropometric measurements will be refined. A structured questionnaire will be used to gather disease history, family history of diabetes, and related information. Comprehensive diabetes-related laboratory screening and complication assessments will be conducted. A standardized biobank will be established, including blood and urine samples from the Da Qing Offspring Study, to support future research on epigenetics, metabolomics, and other mechanisms.
Conditions
- Diabetes Mellitus
- Cardiovascular Diseases (CVD)
- Offspring, Adult
- Impaired Glucose Tolerance (Prediabetes)
- Prevention
- Cancer
- Comorbidity
- Inter- and Transgenerational Inheritance
Interventions
- BEHAVIORAL
-
Lifestyle interventions
Dietary intervention: 30kcal energy intake per kilogram of body weight per day, increase vegetable intake, control sugar and alcohol intake, encourage overweight and obese people to lose weight, lose 0.5-1kg per month until the weight reaches the target. Exercise intervention: Appropriate physical activity in spare time, 30-40 minutes per day, 5 times a week.
Sponsors & Collaborators
-
Daqing Oil Field Hospital
collaborator OTHER -
China-Japan Friendship Hospital
lead OTHER
Principal Investigators
-
Liping Yu, Doctor · China-Japan Friendship Hospital
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- China
Study Locations
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