Da Qing Offspring Study

NCT06958640 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 5000

Last updated 2025-05-06

No results posted yet for this study

Summary

This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups. Based on the original participants, the study will further include their spouses, first to third-generation offspring, and spouses of the offspring. General demographic information will be collected, and anthropometric measurements will be refined. A structured questionnaire will be used to gather disease history, family history of diabetes, and related information. Comprehensive diabetes-related laboratory screening and complication assessments will be conducted. A standardized biobank will be established, including blood and urine samples from the Da Qing Offspring Study, to support future research on epigenetics, metabolomics, and other mechanisms.

Conditions

  • Diabetes Mellitus
  • Cardiovascular Diseases (CVD)
  • Offspring, Adult
  • Impaired Glucose Tolerance (Prediabetes)
  • Prevention
  • Cancer
  • Comorbidity
  • Inter- and Transgenerational Inheritance

Interventions

BEHAVIORAL

Lifestyle interventions

Dietary intervention: 30kcal energy intake per kilogram of body weight per day, increase vegetable intake, control sugar and alcohol intake, encourage overweight and obese people to lose weight, lose 0.5-1kg per month until the weight reaches the target. Exercise intervention: Appropriate physical activity in spare time, 30-40 minutes per day, 5 times a week.

Sponsors & Collaborators

  • Daqing Oil Field Hospital

    collaborator OTHER
  • China-Japan Friendship Hospital

    lead OTHER

Principal Investigators

  • Liping Yu, Doctor · China-Japan Friendship Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06958640 on ClinicalTrials.gov