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Pericardial Histopathology and COVID-19 Seropositivity

NCT06952179 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 93

Last updated 2025-04-30

No results posted yet for this study

Summary

This prospective study aims to investigate the association between pericardial histopathologic inflammation grades (acute, chronic, or absent) and COVID-19 seropositivity in adult patients undergoing first-time isolated coronary artery bypass grafting (CABG). Pericardial tissue samples were collected during surgery and evaluated histopathologically, while preoperative COVID-19 serological testing was performed. The primary outcome is to determine whether COVID-19 seropositivity is associated with the severity of pericardial inflammation. Patients with prior cardiac surgery, active COVID-19 infection, systemic inflammatory diseases, chronic immunosuppressive therapy, or malignancy were excluded from the study.

Conditions

  • Inflammatory Response
  • COVID-19
  • Pericardial Disease

Sponsors & Collaborators

  • Samsun University

    lead OTHER

Principal Investigators

  • emrah ereren · samsun university Faculty of medicine

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-01
Primary Completion
2024-02-01
Completion
2024-06-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06952179 on ClinicalTrials.gov