Endoscopic Therapy Or Surgery for Early Colon Cancer

Summary

The trial is a randomized head-to-head comparison of the benefits, harms and burdens of endoscopic full-thickness resection (eFTR), a novel, minimally invasive endoscopic treatment modality, for early colon cancer as compared to standard-of-care surgery.

Conditions

• Colon Cancer

Interventions

PROCEDURE

eFTR

endoscopic full thickness resection

PROCEDURE

Surgery

standard-of-care surgery

Sponsors & Collaborators

• Medical University of Gdansk

  collaborator OTHER

• Vestre Viken Hospital Trust

  collaborator OTHER

• Medical Biometry and Epidemiology_- Universitätsklinikum Hamburg Eppendorf

  collaborator UNKNOWN

• Institute of Oncology in Warsaw

  collaborator UNKNOWN

• Karolinska Institutet

  collaborator OTHER

• University Hospital, Limoges

  collaborator OTHER

• University Hospital, Akershus

  collaborator OTHER

• University of Roma La Sapienza

  collaborator OTHER

• Hospital Clinic of Barcelona

  collaborator OTHER

• Leuven University Medical Center

  collaborator UNKNOWN

• University Hospital, Ghent

  collaborator OTHER

• Sørlandet Hospital

  collaborator UNKNOWN

• Northern Norway Regional Health Trust

  collaborator UNKNOWN

• Helse Stavanger HF

  collaborator OTHER_GOV

• Haukeland University Hospital

  collaborator OTHER

• St. Olavs Hospital

  collaborator OTHER

• University of Oslo

  collaborator OTHER

• Frontier Science Foundation

  collaborator UNKNOWN

• Norwegian Department of Health and Social Affairs

  lead OTHER_GOV

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-08-25

Primary Completion

2033-09-01

Completion

2033-09-01

Countries

• Poland

Study Locations