Standardizing Right Hemicolectomy for Colon Cancer

Summary

A surgical intervention might be highly variable amongst surgeons and centers. This variability has a potential relevance concerning clinical outcomes.

For right-sided colon cancer, the laparoscopic right hemicolectomy (LRHC) knows substantial variation. Especially since the surgical technique has been evolving during the latest decade with the introduction of intracorporeal anastomosis, a dissection technique within the correct embryological planes (complete mesocolic excision) and central vascular ligation of the segmental branches at its origin, resulting in an optimal lymph node dissection.

Given the insights from recent studies showing the association between quality of surgery and relevant clinical outcomes, there is a great need for a formative quality assessment of LRHC. Detailed objective assessment of the LRHC is currently not performed in clinical practice nor in surgical training. Quality assessment of LRHC has great potential to improve surgical training and furthermore, implementation of a standardized technique will ultimately lead to better quality of care for patients suffering from right-sided colon cancer.

The main objective of this study is to improve surgical outcomes for patient with right-sided colon cancer by a prospective sequential interventional cohort study that aims to standardize the surgical technique with subsequent controlled implementation after standardized review of the current practice in a nationwide multicenter setting. The primary endpoint is the 30-day morbidity according to the Clavien-Dindo classification system.

Conditions

• Colonic Carcinoma
• Laparoscopic Right Hemicolectomy
• Standardisation
• Training
• Delphi Study
• Implementation
• Consolidation
• Assessment

Interventions

PROCEDURE

Implementation standardised laparoscopic right hemicolectomy with proctoring

Implementation standardised laparoscopic right hemicolectomy with proctoring

PROCEDURE

Implementation standardised laparoscopic right hemicolectomy without proctoring

Implementation standardised laparoscopic right hemicolectomy without proctoring

Sponsors & Collaborators

• Prof. dr. P.J. Tanis, colorectal surgeon

  collaborator UNKNOWN

• Dr. B.R. Toorenvliet, colorectal surgeon

  collaborator UNKNOWN

• D. Miskovic, St Marks hospital London, UK

  collaborator UNKNOWN

• S. Benz, Klinikverbund SuedWest, Böblingen, Germany

  collaborator UNKNOWN

• F. Aigner, Krankenhaus der Barmherzigen Bruder, Graz, Austria

  collaborator UNKNOWN

• C.A. Bertelsen, Hillerød University Hospital, Copenhagen, Denmark

  collaborator UNKNOWN

• Drs. A.A.J. Grüter

  collaborator UNKNOWN

• Dr. U.K. Coblijn

  collaborator UNKNOWN

• Dr. H.L. van Westreenen

  collaborator UNKNOWN

• Dr. C. Sietses

  collaborator UNKNOWN

• Prof. dr. E.C.J. Consten

  collaborator UNKNOWN

• Dr. A.W.H. van de Ven

  collaborator UNKNOWN

• Dr. P. van Duijvendijk

  collaborator UNKNOWN

• Dr. S. van Aalten

  collaborator UNKNOWN

• Dr. F. den Boer

  collaborator UNKNOWN

• Dr. J.W.A. Leijtens

  collaborator UNKNOWN

• Dr. C. Hoff

  collaborator UNKNOWN

• Dr. O. van Ruler

  collaborator UNKNOWN

• Dr. G. D. Slooter

  collaborator UNKNOWN

• Prof. dr. J. Lange

  collaborator UNKNOWN

• Prof. dr. G.J. Kleinrensink

  collaborator UNKNOWN

• Amsterdam UMC, location VUmc

  lead OTHER

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

SEQUENTIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-07-01

Primary Completion

2022-07-01

Completion

2027-07-01

Countries

• Netherlands

Study Locations