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EIT-Guided Ventilator Settings in AHRF

NCT06936618 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2025-04-27

No results posted yet for this study

Summary

This exploratory study aims to investigate the effect of Electrical Impedance Tomography (EIT)-guided ventilator settings on mechanical power in patients with acute hypoxemic respiratory failure (AHRF), including both ARDS and non-ARDS conditions. Mechanical power, a key factor associated with ventilator-induced lung injury (VILI), will be measured before and after EIT-guided PEEP titration. The study will evaluate feasibility and changes in lung mechanics, gas exchange, and EIT parameters. A total of 17 patients requiring invasive mechanical ventilation will be enrolled at Siriraj Hospital, Mahidol University.

Conditions

  • Acute Hypoxemic Respiratory Failure
  • Acute Respiratory Distress Syndrome (ARDS)
  • Mechanical Power
  • Ventilator Induced Lung Injury
  • Electrical Impedance Tomography (EIT)

Interventions

DEVICE

Electrical Impedance Tomography (EIT), Enlight 2100

Patients will undergo ventilator adjustments using EIT-guided PEEP titration to optimize mechanical power and lung mechanics.

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Ranistha Ratanarat, Associated Professor, MD · Siriraj Hospital

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-17
Primary Completion
2026-10-31
Completion
2026-12-31

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06936618 on ClinicalTrials.gov