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Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye

NCT06921525 · Status: NOT_YET_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2025-04-10

No results posted yet for this study

Summary

This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED. By focusing on changes in tear IL-8 and IL-17 levels, the study seeks to provide insights into the differential mechanisms of these two treatments and their potential in addressing inflammation-driven DED.

Conditions

  • Dry Eye

Interventions

DRUG

Tea Tree Oil Topical Application Oil

Tea tree oil (TTO), derived from the leaves of Melaleuca alternifolia,

DRUG

Azithromycin Ophthalmic Solution

Azithromycin has demonstrated efficacy in improving meibomian gland function and reducing inflammation and improving symptoms of dryness of the eye

Sponsors & Collaborators

  • Tanta University

    collaborator OTHER

  • Ehab Mohamed Elsayed Mohamed Saad

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2025-07-01
Completion
2025-08-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06921525 on ClinicalTrials.gov