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Lipids of the Human Tear Film and Their Effect on Tear Stability

NCT00803452 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2017-12-22

Study results available
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Summary

This prospective, randomized, comparative clinical trial evaluates the effect of either oral doxycycline, oral essential fatty acid, or topical azithromycin to modify the secretions of the meibomian gland in subjects with meibomian gland dysfunction and/or dry eye disease.

Conditions

  • Blepharitis

Interventions

DRUG

doxycycline

Oral doxycycline 100mg bid

DRUG

azithromycin

topical 1% azithromycin daily to eye

Sponsors & Collaborators

  • University of Louisville

    lead OTHER

Principal Investigators

  • Gary N Foulks, MD · University of Louisville

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-07-31
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00803452 on ClinicalTrials.gov