Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function
NCT06906536 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2025-04-04
Summary
The goal of this study is to clarify mechanisms of acute intermittent hypoxia and to examine the effect on lower limb function in persons with chronic, incomplete spinal cord injury.
Conditions
- INCOMPLETE SPINAL CORD INJURY (ASIA D)
- Able Bodied
Interventions
- OTHER
-
Acute Intermittent Hypoxia (AIH)
4 consecutive days of 15, 1.5 min episodes at 9% O2 (AIH) alternating with 21% O2 at 1 min intervals
Sponsors & Collaborators
-
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
collaborator NIH -
University of Colorado, Denver
collaborator OTHER -
University of Colorado, Boulder
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-03-01
- Primary Completion
- 2026-03-31
- Completion
- 2026-08-31
Countries
- United States
Study Locations
More Related Trials
-
Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury
NCT05966896 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training
NCT03922802 ·Status: COMPLETED ·Phase: NA
-
Study Effects of Intermittent Hypoxia on Restoring Hand Function Following SCI
NCT01272336 ·Status: COMPLETED ·Phase: PHASE1
-
Intermittent Hypoxia to Enhance Motor Function After Spinal Cord Injury
NCT03071393 ·Status: COMPLETED ·Phase: NA
-
Hypoxia Pathways for Early Recovery After Spinal Cord Injury
NCT07002437 ·Status: RECRUITING ·Phase: NA
-
Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI
NCT01272349 ·Status: COMPLETED ·Phase: PHASE1
-
AIH-induced Walking Recovery After Subacute SCI
NCT02632422 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI
NCT04854057 ·Status: TERMINATED ·Phase: NA
-
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
NCT04017767 ·Status: COMPLETED ·Phase: NA
-
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
NCT02323945 ·Status: RECRUITING ·Phase: NA
-
Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair
NCT03433599 ·Status: RECRUITING ·Phase: NA
-
Acute Intermittent Hypoxia and Body Weight Supported Treadmill Training for Incomplete Spinal Cord Injury Patients
NCT02441179 ·Status: COMPLETED ·Phase: NA
-
Impact of Intermittent Hypoxia and Prednisolone on Motor Performance in Persons With SCI
NCT03752749 ·Status: COMPLETED ·Phase: NA
-
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
NCT06691165 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)
NCT06406855 ·Status: RECRUITING ·Phase: NA
-
Device-induced Intermittent Hypoxia in Persons With Incomplete Spinal Cord Injury
NCT05491837 ·Status: COMPLETED ·Phase: NA
-
Intermittent Hypoxia in Persons With Multiple Sclerosis
NCT06276634 ·Status: RECRUITING ·Phase: NA
-
Multimodality Intervention for Function and Metabolism in SCI
NCT03576001 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
NCT01095380 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
NCT03762655 ·Status: TERMINATED ·Phase: NA
-
Hyperbaric Oxygen and Orthopedic Comprehensive Treatment for Traumatic Incomplete Spinal Cord Injury in the Plateau
NCT03112941 ·Status: COMPLETED ·Phase: NA
-
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
NCT02323698 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Spinal Cord Stimulation for Chronic and Intractable Back Pain
NCT00370695 ·Status: TERMINATED ·Phase: NA
-
Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury
NCT05982171 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity
NCT05940636 ·Status: COMPLETED ·Phase: NA