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Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS

NCT06889454 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2025-11-19

No results posted yet for this study

Summary

The aim of the present study is to investigate a) the presence of subclinical markers of vascular, myocardial and endothelial function in women with PCOS b) the acute alterations in these markers during the oral glucose tolerance test (OGTT) c) the impact of potential treatment interventions in these markers.

Conditions

  • PCOS
  • Hyperinsulinism
  • Hyperandrogenism
  • Metabolic Syndrome

Interventions

DRUG

GLP-1 receptor agonist

30 women will receive lifestyle modification and GLP-1 receptor agonists

DRUG

Oral contraceptive

30 women will receive lifestyle modification and oral contraceptive

DRUG

Metformin

30 women will receive lifestyle modification and metformin

OTHER

Lifestyle modification

30 women will receive only lifestyle modification

Sponsors & Collaborators

  • Attikon Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-01
Primary Completion
2025-02-01
Completion
2026-02-01
FDA Drug
Yes

Countries

  • Greece

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06889454 on ClinicalTrials.gov