Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
NCT06865222 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2025-08-14
Summary
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).
Conditions
- Post COVID-19 Condition
Interventions
- PROCEDURE
-
Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 2 weeks
The Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) will be administered through an FDA-approved Transcranial Magnetic Stimulation (TMS) medical device. Results of the baseline EEG will be uploaded to NoetherTech's EMBP software on the Mayo Clinic campus, and transferred to Noethertech servers for TMS parameter determination TMS treatment will be one 30 min session per day, 5 days per week (Monday-Friday), for 2 weeks.
- PROCEDURE
-
Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 4 weeks
The Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) will be administered through an FDA-approved Transcranial Magnetic Stimulation (TMS) medical device. Results of the baseline EEG will be uploaded to NoetherTech's EMBP software on the Mayo Clinic campus, and transferred to Noethertech servers for TMS parameter determination TMS treatment will be one 30 min session per day, 5 days per week (Monday-Friday), for 4 weeks.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Ryan T. Hurt, M.D. · Mayo Clinic
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-22
- Primary Completion
- 2027-01-31
- Completion
- 2027-04-30
Countries
- United States
Study Locations
More Related Trials
-
Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder
NCT02990793 ·Status: COMPLETED ·Phase: NA
-
Psychosis TMS Study
NCT05857137 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Spectral Correlates of Impulsivity in Patients With Traumatic Brain Injury
NCT04239274 ·Status: WITHDRAWN ·Phase: NA
-
Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State
NCT04010461 ·Status: COMPLETED ·Phase: NA
-
Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome
NCT07211919 ·Status: COMPLETED
-
NQ TMS for MDD Therapy Using 1 Day x 3 Sessions Protocol for Adult Patient
NCT06772987 ·Status: COMPLETED ·Phase: NA
-
Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment
NCT06385405 ·Status: RECRUITING ·Phase: NA
-
Modeling TMS-induced Cortical Network Activity
NCT05288959 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Magnetic Brain Stimulation in the Treatment of Mild Cognitive Impairment
NCT02420522 ·Status: SUSPENDED ·Phase: NA
-
Brain-oscillation Synchronised Stimulation of the Prefrontal Cortex
NCT02920840 ·Status: COMPLETED ·Phase: NA
-
rTMS for PTSD Comorbid With Major Depressive Disorder
NCT02273063 ·Status: COMPLETED ·Phase: NA
-
Transcranial Magnetic Stimulation (TMS) to Treat mTBI and PTSD
NCT02458521 ·Status: UNKNOWN ·Phase: NA
-
Mini Theta Burst TMS in MDD Patients
NCT04014959 ·Status: COMPLETED ·Phase: NA
-
Testing a Transdiagnostic TMS Treatment Target
NCT06282146 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Transcranial Pulse Stimulation (TPS) in Post-COVID-19
NCT06178952 ·Status: RECRUITING ·Phase: NA
-
Pilot TMS in Mild TBI
NCT06999304 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Accelerated TMS for Perinatal Depression
NCT06968390 ·Status: RECRUITING ·Phase: NA
-
tDCS in Post-COVID Syndrome: Comparison of Two Targets
NCT05753202 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Post-traumatic Stress Disorder (PTSD)
NCT00685152 ·Status: COMPLETED ·Phase: NA
-
High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD
NCT02873299 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Transcranial Direct Current Stimulation (tDCS) for Post COVID-19 Fatigue
NCT04876417 ·Status: COMPLETED ·Phase: NA
-
Symptom-specific TMS Targets for Depression and Anxiety
NCT04604210 ·Status: COMPLETED ·Phase: PHASE2
-
tDCS in the Management of Post-COVID Disorders
NCT06074848 ·Status: RECRUITING ·Phase: PHASE2
-
Investigating the Physiology of Targeted Theta-burst Neuromodulation
NCT02616835 ·Status: COMPLETED ·Phase: NA
-
Effect of Non-Invasive Neuromodulation on Primary Chronic Pain, Including Post-COVID-19
NCT06689345 ·Status: ENROLLING_BY_INVITATION ·Phase: NA