Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis

Summary

Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and physical consequences that affect the quality of life, whose cause is unknown, but usually affects the respiratory system, and occurs mostly in young and middle-aged adults. Lung involvement, seen in 95% of patients, causes limitation of lung capacity and decrease in inspiratory muscle strength, which are important factors that lead to an increase in dyspnea and a decrease in walking distance. In addition to respiratory muscle weakness, skeletal muscle dysfunction is also frequently observed. The most common symptoms in sarcoidosis are dyspnea and fatigue. When the current literature is examined, it can be seen that studies on non-pharmacological treatment methods in Sarcoidosis are quite limited. Although relatively common in Chronic Obstructive Pulmonary Disease (COPD), various studies conducted in patients with Bronchiectasis, Pulmonary Arterial Hypertension and Asthma have shown that yoga results in a decrease in dyspnea and fatigue, and an increase in pulmonary functions and exercise capacity. On the other hand, no study has been found on yogic techniques in Sarcoidosis. Aim of this study is to investigate the effects of yogic techniques and conventional physiotherapy program on pulmonary functions, body oxygen level test (BOLT), exercise capacity (6MWT), anxiety, depression, fatigue, dyspnea perception, sleep quality, and quality of life in sarcoidosis cases at different stages. In these patients known to have multisystem involvement, holistic approaches gain importance due to the nature of the disease.

Conditions

• Sarcoidosis
• Pulmonary Rehabilitation
• Yoga

Interventions

PROCEDURE

traditional physiotherapy group

* Resistance training: It is planned to give strengthening exercises for the upper and lower extremities (quadriceps, hamstrings, gluteus medius, gastrosoleus, deltoids, triceps and biceps brachii) with the resistive exercise band. The fatigue severity perceived by the patients during the exercises is aimed to be 4-6 according to the Modified Borg scale * Pursed-lip breathing training (10 repetitions) * Chest breathing exercise (10 repetitions) * Diaphragmatic breathing exercise (10 repetitions) * Thoracic expansion exercises (10 repetitions - apical expansion, unilateral basal expansion, bilateral basal expansion, posterior basal expansion) Additionally In terms of aerobic training, free walking will be provided 3 days a week. (Based on distance determined by 6 DYT)

PROCEDURE

yoga program

Pranayamic techniques: Nadi Shodhana: 2 sets of nadi shodhana pranayama consisting of 8 breathing cycles will be applied. Ujjai: Two sets of ujjayi technique consisting of 10 breathing cycles with an inhalation:exhalation ratio of 1:2 in each session will be applied with a 1-minute rest period between sets. Bhramari: Two sets of bhramari pranayama consisting of 10 breathing cycles will be applied with a low respiratory rate with a 1-minute rest period between sets. Sukha Pranayama : It will be applied 5:5 inhalation:exhalation ratio for 5 minutes. Kapalabhati: 15 quick breaths in 10 seconds followed by a 20-second break (30 breaths per minute in total) will be practiced for 3 minutes Asanas: Sukhasana Bharadvajasana Marjaryasana- Bitilasana Bhujaganasana Kapotasana Hasta uttanasana Virabhadrasana I In addition, free walking will be given 3 days a week in terms of aerobic training. (Based on distance determined by 6 DYT)

Sponsors & Collaborators

• Istanbul Saglik Bilimleri University

  collaborator OTHER

• Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital

  collaborator OTHER

• Saglik Bilimleri Universitesi

  lead OTHER

Principal Investigators

• Zuhal D TAKİNACI, PT, Asst Prof · University of Health science

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-11-30

Primary Completion

2025-04-01

Completion

2025-05-30

Countries

• Turkey (Türkiye)

Study Locations