MedTrace Logo

Mg Sulfate Versus Dexmedetomidine on Cerebral Oxygen Saturation

NCT06848595 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2025-02-27

No results posted yet for this study

Summary

This study is to evaluate the effects of dexmedetomidine and magnesium sulfate on cerebral oxygen saturation in patients undergoing spine surgeries as adjuvant to general anesthesia guided by cerebral oximetry. The main aims to are Incidence of cerebral desaturation events and duration of cerebral desaturation events.

Conditions

  • Cerebral Desaturation Events
  • Spine Surgeries

Interventions

PROCEDURE

spine surgery

spine surgery in prone position

DRUG

Magnesium sulfate

Patients will receive loading dose of 40 mg/kg of magnesium sulfate diluted in 50 ml of 0.9% saline IVI will be given in 10 min before anesthesia induction then continuous infusion of 10 mg/kg/hour during the surgery.

DRUG

Dexmedetomidine

Patients will receive loading dose of 1 mcg/kg dexmedetomidine diluted in 50 ml of saline 0.9% IVI will be given in 10 min before anesthesia induction then continuous infusion of 0.5 mcg/kg/hour during the surgery.

DRUG

Normal Saline (0.9% NaCl)

Patients will receive the same volume of normal saline.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Ahmed Said Elgebaly, professor · Tanta University

  • Shimaa Farouk Abdelkader, professor · Tanta University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-23
Primary Completion
2027-01-20
Completion
2027-01-31

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06848595 on ClinicalTrials.gov