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Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion

NCT02854904 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2016-08-23

No results posted yet for this study

Summary

Alpha-agonist in anesthesia display immunomodulatory effect in addition to antiadrenergic control. This effect of the immune system can be a key to a better perioperative safety and quality.

The association of dexmedetomidine at general anesthesia adds up organic protection and inflammatory control to a surgery trauma owing to antinociception and immunomodulatory effect.

The aim this study is evaluate if the association of dexmedetomidine at general anesthesia standing effective immunomodulatory control to trauma and improve changes at outcomes in patients undergoing to spinal fusion.

Conditions

  • Spine; Arthrosis
  • Spondylolysis
  • Spondylolysis, Multiple Sites in Spine
  • Spondylolisthesis

Interventions

DRUG

Dexmedetomidine intervention

Immune effect of alpha-2 agonist to arthrodesis. Dexmedetomidine as a immune control anesthesic in patients undergoing to arthrodesis. Alpha-2 agonist to general anaesthesia.

DRUG

Placebo

Placebo controlled

Sponsors & Collaborators

  • University of Brasilia

    collaborator OTHER

  • Sarah Network of Rehabilitation Hospitals

    lead OTHER

Principal Investigators

  • Luciano P Miranda · Sarah Network of Rehabilitation Hospitals

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-08-31
Primary Completion
2016-11-30
Completion
2017-06-30

Countries

  • Brazil

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02854904 on ClinicalTrials.gov