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Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty

NCT06837012 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 106

Last updated 2025-02-20

No results posted yet for this study

Summary

Analgesic effect of 20mg Duloxetine was evaluated at regular short term intervals in patients without central sensitivity and undergoing bilateral single sitting total knee arthroplasty for tricompartmental osteoarthritis using standardised patient related outcome measures like the visual analogue score.

Conditions

  • Osteoarthritis of Knee
  • Central Sensitization
  • Central Sensitisation

Interventions

DRUG

Duloxetine - low dose

Only patients who underwent single bilateral Total knee arthroplasty and WITHOUT central sensitisation were evaluated

DRUG

Placebo

starch capsules identical in appearance and weight to the duloxetine capsules

Sponsors & Collaborators

  • The Grant Medical College & Sir J.J. Group of Hospitals

    collaborator OTHER_GOV

  • Orthopaedic Arthroscopy Knee and Shoulder Clinic

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2022-07-31
Completion
2022-07-31
FDA Drug
Yes

Countries

  • India

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06837012 on ClinicalTrials.gov