MedTrace Logo

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

NCT06809998 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-05-01

No results posted yet for this study

Summary

Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.

Conditions

  • Total Knee Anthroplasty
  • Osteoarthritis(Primary)
  • Osteoarthritis (OA) of the Knee
  • Bilateral Knee Osteoarthritis

Interventions

DRUG

Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).

Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).

OTHER

Band-Aid

Band-Aid

Sponsors & Collaborators

  • Unity Health Toronto

    lead OTHER

Principal Investigators

  • Amir Khoshbin, MD, FRCS (C) · Unity Health Toronto

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-24
Primary Completion
2026-07-30
Completion
2027-07-30

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06809998 on ClinicalTrials.gov