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The Ventilation During In-hospital Cardiac Arrest Study

NCT06809309 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 900

Last updated 2026-03-30

No results posted yet for this study

Summary

The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult patients.

The main questions it aims to answer are:

What ventilation volume during CPR is associated with the highest chance of return of spontaneous circulation (ROSC)? What ventilation rate during CPR is associated with the highest chance of ROSC?

Researchers will compare different levels of ventilation rates and volumes that are blindly measured during CPR to see how the observed rates and volumes are associated with survival outcomes and complications.

Conditions

  • Cardiac Arrest (CA)
  • In-Hospital Cardiac Arrest
  • Heart Arrest

Interventions

OTHER

Positive pressure ventilation during cardiopulmonary resuscitation

The primary exposures of interest are the observed ventilation rate, tidal volume and minute ventilation during cardiopulmonary resuscitation. Ventilation data are obtained by inspiratory and expiratory air flow measurements using the EOlife (Archeon, Besançon, France) to which healthcare providers are blinded.

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Johannes Wittig, MD · Department of Clinical Medicine, Aarhus University, Denmark; Department of Medicine, Randers Regional Hospital, Randers, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Denmark

  • Kasper G Lauridsen, MD, PhD · Department of Clinical Medicine, Aarhus University, Denmark; Department of Medicine, Randers Regional Hospital, Randers, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Denmark;

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-01
Primary Completion
2027-04-30
Completion
2027-06-30

Countries

  • Denmark
  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06809309 on ClinicalTrials.gov