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Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study

NCT06808841 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-02-05

No results posted yet for this study

Summary

1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway.
2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow.
3. To investigate the relationship between different doses of opioids and BMP-6 and perioperative cardiovascular adverse events in patients with lower extremity fracture surgery.

Conditions

  • Myocardial Injury

Interventions

DRUG

Sufentanil injection

Different concentrations of sufentanil were administered to three different subgroups of patients in the same way

DRUG

Placebo

Placebo

Sponsors & Collaborators

  • Second Hospital of Shanxi Medical University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-05
Primary Completion
2025-05-10
Completion
2025-05-10

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06808841 on ClinicalTrials.gov