Clinical Study of Envafolimab Combined With Fruquintinib and Chemotherapy for Neoadjuvant Treatment of Gastric Cancer
NCT06791083 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2025-01-24
Summary
To observe and evaluate the neoadjuvant treatment of Envafolimab combined with Fruquintinib and chemotherapy for locally advanced gastric/gastroesophageal junction carcinoma
Conditions
Interventions
- DRUG
-
Envafolimab
150mg/m2 , IH, d1;Q3W
- DRUG
-
5 mg ,po,QD,d1-d14;Q3W
Sponsors & Collaborators
-
First Affiliated Hospital of Fujian Medical University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-06-20
- Primary Completion
- 2025-12-31
- Completion
- 2027-05-31
Countries
- China
Study Locations
More Related Trials
-
A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer
NCT06464601 ·Status: NOT_YET_RECRUITING
-
Fruquintinib Combined With TAS102 for Advanced Gastric Cancer
NCT06102785 ·Status: RECRUITING
-
Fruquintinib Combined with Sintilimab As Second-line Therapy for Gastric or Gastro-esophageal Junction Adenocarcinoma
NCT05625737 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Fruquintinib Plus SOX as Neoadjuvant Therapy for Locally Advanced Gastric Adenocarcinoma
NCT05122091 ·Status: RECRUITING ·Phase: PHASE2
-
Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric Cancer
NCT06888037 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Fruquintinib Combined With PD-1 Inhibitor and FOLFOX as First-Line Treatment For Advanced Gastric Cancer
NCT06871527 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Fruquintinib in Combination With PD-1 Inhibitors as First-line Maintenance Therapy for Advanced HER-2 Negative Gastric Cancer: a Single-arm, Prospective, Exploratory Clinical Study
NCT05721651 ·Status: RECRUITING ·Phase: PHASE2
-
Conversion Therapy of Fruquintinib in Combination With Sintilimab and SOX in Unresectable Gastric Cancer
NCT05177068 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced Cancer
NCT06094868 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of Fruquintinib Plus Chemotherapy for Postoperative Treatment of HER2-Negative Gastric Cancer With Poor TRG
NCT06774222 ·Status: RECRUITING ·Phase: PHASE2
-
Study of The Second-line Treatment of Advanced Gastric / Gastroesophageal Junction Adenocarcinoma With Envafolimab and Lenvatinib Combined With Paclitaxel-albumin
NCT06030934 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Treatment Based on Gastric Cancer Molecular Subtyping.
NCT06376773 ·Status: COMPLETED
-
A Phase Ib/2 Clinical Study of Fruquintinib Combined With Paclitaxel in the Treatment of Advanced Gastric Cancer
NCT02415023 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Fruquintinib Combined With Toripalimab and SOX Regimen in the First-line Treatment of Advanced Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
NCT05024812 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer
NCT01928290 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2) Negative Gastroesophageal Cancer
NCT01590719 ·Status: COMPLETED ·Phase: PHASE2
-
Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer
NCT06329973 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Fruquintinib Combined With Sintilimab and Stereotactic Body Radiation Therapy (SBRT) for the Second-line and Higher-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Oligometastatic Progression
NCT06977061 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer
NCT07334431 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Conversion Therapy of Sintilimab in Combination With Fruquintinib and Chemotherapy Versus Sintilimab and Chemotherpay in Stage IV Gastric Cancer
NCT06454435 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer
NCT06459921 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.
NCT05111626 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of The Second-line Treatment of Advanced Gastric / Gastroesophageal Junction Adenocarcinoma With Cadonilimab and Fruquintinib Combined With Paclitaxel-albumin
NCT06406426 ·Status: RECRUITING ·Phase: PHASE2
-
Sintilimab in Combination with Chemotherapy ± Local Treatment for Om-G/GEJ
NCT06739161 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
NCT07221149 ·Status: RECRUITING ·Phase: PHASE2/PHASE3