Understanding the Role of Large Extracellular Vesicles in Lymphomas and Lymphoproliferative Disorders: the "Off the Beaten Track" Liquid Biopsy
NCT06782854 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 102
Last updated 2025-01-20
Summary
This study aims to investigate the role of extracellular vesicles as diagnosic and prognostic biomarkers in patients with lymphomas or lymphoproliferative disorders. In particular, circulating extracellular vesicles, thanks to their cargo of proteins, lipids, and nucleic acids, play a role in the communication between cells. Since it has been described that these vesicles are able to influence also immune cells, the study of their functions may lead to the discovery of new mechanisms underlying this type of diseases.
Conditions
- Diffuse Large B-Cell Lymphoma
- Follicular Lymphoma
- Marginal Zone Lymphoma(MZL)
- Mycosis Fungoides
- Chronic Lymphocytic Leukemia
- Hairy Cell Leukemia (HCL)
- T Cell Lymphoma
- Multiple Mieloma
Sponsors & Collaborators
-
IRCCS Azienda Ospedaliero-Universitaria di Bologna
lead OTHER
Principal Investigators
-
Lucia Catani, PhD · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-02-21
- Primary Completion
- 2023-02-20
- Completion
- 2024-11-17
Countries
- Italy
Study Locations
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