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Cancer Prevalence and Outcomes in Individuals With HIV and AIDS: Multicenter BUHASDER Study

NCT06774495 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 154

Last updated 2025-04-24

No results posted yet for this study

Summary

AIDS-defining cancers reported a 70% drop in the 1990s following the advent of triple antiretroviral therapy in the USA. With increased survival, the proportion of non-AIDS-defining cancers increases with age, making cancer a leading cause of death among individuals with HIV infection in developed countries, with higher cancer-related mortality rates in this group. In Turkey, studies have reported HIV-associated non-Hodgkin lymphoma cases, and a multicentre study documented 37 cancer cases from 1998 to 2016.

This study aims to determine the prevalence of cancer in individuals with HIV and AIDS in Turkey over the past decade, examining the age-related distribution and risk factors for HIV-related and unrelated cancers. Additionally, the mortality rates and comorbidities affecting mortality will be assessed. The findings will be compared with the Turkish Statistical Institute's data on cancer prevalence, type, and mortality.

Conditions

Sponsors & Collaborators

  • Dokuz Eylul University

    collaborator OTHER

  • Kocaeli University

    lead OTHER

Principal Investigators

  • Özlem Güler, Assist Prof. · Kocaeli University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-12
Primary Completion
2025-04-23
Completion
2025-04-23

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06774495 on ClinicalTrials.gov