MedTrace Logo

UK Heart Failure With Preserved Ejection Fraction

NCT05441839 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10000

Last updated 2025-05-06

No results posted yet for this study

Summary

Heart failure occurs when the heart is no longer able to pump blood around the body properly. It can cause breathlessness, swollen feet and ankles, and tiredness. In about half of patients with heart failure, one measure of the heart's pumping function, called the 'ejection fraction', is normal. This type of heart failure is called heart failure with preserved ejection fraction, or HFpEF.

HFpEF remains poorly understood. It is not clear why some people develop HFpEF, or what determines the severity of the condition. Treatment options may be limited.

UK HFpEF is a study that aims to gain a better understanding of why people develop HFpEF, develop better tests to diagnosis it, identify and test new treatments, and follow the health of the people taking part over many years.

Conditions

  • Heart Failure With Preserved Ejection Fraction (HFpEF)

Sponsors & Collaborators

  • Pumping Marvellous Foundation

    collaborator UNKNOWN

  • British Society for Heart Failure

    collaborator UNKNOWN

  • National Institute for Health Research, United Kingdom

    collaborator OTHER_GOV

  • British Heart Foundation Data Science Centre

    collaborator UNKNOWN

  • Manchester University NHS Foundation Trust

    lead OTHER_GOV

Principal Investigators

  • Chris Miller, MBChB FRCP · Manchester University NHS Foundation Trust

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-07
Primary Completion
2037-06-01
Completion
2037-06-01

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05441839 on ClinicalTrials.gov