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Mechanisms and Phenotypes of Hypertension in Patients in Chronic Hemodialysis

NCT06764277 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2026-02-03

Study results available
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Summary

The goal of this study is to evaluate interdialytic blood pressure changes of the patients in chronic hemodialysis.

The main question to be answered is: What is the relative importance of weight gain, the renin angiotensin system, the sympathetic nervous system and inflammatory immune reactivity in the interdialytic hypertension of patients in chronic hemodialysis, The participants will have hemodynamic evaluation (cardiac output and peripheral vascular resistance) at the end of dialysis, ambulatory monitoring of blood pressure in the interdialytic period. Serum samples will be collected at the end of dialysis and before the start of the next dialysis, 2-3 days later.

Conditions

  • Arterial Hypertension
  • Hemodialysis

Interventions

OTHER

There will be no intervention

There will be no intervention. This is an observational studies and 3 groups will be organized depending on the level of ABP in the interdialytic period

Sponsors & Collaborators

  • Bernardo Rodríguez Iturbe

    lead OTHER

Principal Investigators

  • Bernardo RODRIGUEZITURBE, MD, PhD · Department of Nephrology, Instituto Nacional de Ciencias Medicas y Nutrición "Salvador Zubirán"

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-14
Primary Completion
2024-12-20
Completion
2025-06-06

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06764277 on ClinicalTrials.gov