MedTrace Logo

The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Metabolism and Glycemic Control in Healthy Active Adults

NCT06737224 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2025-03-07

No results posted yet for this study

Summary

Many individuals engage in fasting for its purported health benefits but the effects of fasting on immune cell and whole body metabolism are not well understood in humans. Moreover, how exercising during a prolonged fast impacts immunometabolic outcomes is unclear. This study will determine how a 2 day fast - performed with or without daily exercise - impacts immune cell bioenergetics, immune cell function, and whole-body glycemic control in healthy active individuals.

Conditions

  • Fasting
  • Immune Function
  • Glucose Tolerance

Interventions

OTHER

Fasting + Exercise (FAST+EX): fasting + exercise condition

Participants will complete a 48-hour fast. One hour of exercise will be performed on each morning of the fast.

OTHER

Fasting only (FAST): Non-exercise fasting condition

Participant will complete a 48-hour fast. No structured exercise will be performed during each of the fasting days.

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
19 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-10
Primary Completion
2025-08-01
Completion
2025-08-01

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06737224 on ClinicalTrials.gov