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An Algorithmic Approach to Preoxygenation

NCT06736197 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 378

Last updated 2024-12-16

No results posted yet for this study

Summary

The aim of this randomized controlled trial is to evaluate an algorithmic approach to gradually adding pressure-supported ventilation and end-tidal positive pressure when conventional tidal volume breathing is insufficient for adequate preoxygenation. The main question it aims to answer is:

* Will the proportion of patients receiving preoxygenation increase?
* Will the duration of preoxygenation decrease?

Participants will;

* 200 patients who were planned to undergo general anesthesia for elective surgeries
* aged between 18 and 65 years
* ASA 1-2 physical status
* ETO2 \<90% at the end of the 3rd minute with spontaneous tidal volume breathing

Conditions

  • Preoxygenation
  • Anaesthesia Induction
  • Non-invasive Positive Pressure Ventilation

Interventions

PROCEDURE

Group TVB

Patients who could not reach ETO2 value 90 with tidal volume breathing for 3 min were included in Group TVB tidal volume breathing was continued for 2 min.

PROCEDURE

Group PSV

Preoxygenation was continued by providing 6cmH2O pressure support to the patients included in this group.

PROCEDURE

Group PSV+PEEP

At the 4th minute, preoxygenation was continued by adding 4 cmH2O positive end-expiratory pressure to the same 6 cmH2O pressure support for 1 min in patients whose end-tidal O2 value still reached 90% and who were included in this group.

Sponsors & Collaborators

  • Pamukkale University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-01
Primary Completion
2021-03-01
Completion
2021-06-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06736197 on ClinicalTrials.gov