Evaluation The Effect of NB-UVB and Methotrexate on The Level of Serum Gelsolin in Psoriatic Patients
NCT06712238 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2024-12-02
Summary
Psoriasis is a common chronic, immune-mediated, skin disease with a significantly negative impact on patients' quality of life. It is one of papulosquamous diseases defined by erythematous plaques with silvery scales.
The interplay among cytokines released by dendritic, Th1, Th2, and Th17 cells leads to the clinical manifestations seen in psoriasis. Although discovering novel biomarkers for psoriasis is challenging step., it may play an essential role in diagnosis, severity assessment and prediction of treatment outcome and prognosis of the disease
Conditions
- Psoriatic Conditions
Interventions
- PROCEDURE
-
NB-UVB
Comparison between serum Level of Gelsolin (GSN) in Psoriatic Patients and controls and correlate its level with PASI.
Sponsors & Collaborators
-
Aswan University
lead OTHER
Principal Investigators
-
Moustafa Adam Ali El Taieb, Professor · Dermatology, Venereology and Andrology.Faculty of Medicine, Aswan University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 15 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-06-10
- Primary Completion
- 2025-06-01
- Completion
- 2025-06-10
Countries
- Egypt
Study Locations
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