The Effect of NB-UVB on Interleukin-36 Levels in Psoriasis
NCT03526705 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2019-07-23
Summary
Psoriasis is an immune-mediated skin disease that affects 1-2 % of the population. Several cytokines have been found to be involved in the complex pathogenesis of this disease. Il- 36 is one of the cytokines sharing in psoriasis pathogenesis, as its levels are elevated in psoriatic plaques. Cathepsin G is known to activate Il- 36 and promote inflammation in psoriasis.NB-UVB is one of the important treatment modalities for psoriasis.
The aim of this study is to detect the effect of NB-UVB on the lesional levels of IL-36 in psoriasis.
Conditions
Interventions
- DEVICE
-
NB-UVB
Phototherapy
Sponsors & Collaborators
-
Cairo University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-15
- Primary Completion
- 2020-01-15
- Completion
- 2020-01-15
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