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Effect of Exercise on Irisin Levels of Hypothyroid Rats

NCT06699069 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-11-21

No results posted yet for this study

Summary

The aim of study was to evaluate the role of exercise on serum irisin levels in hypothyroid rats.

Conditions

Interventions

OTHER

Control or Euthyroid group

Fed on normal standard diet

OTHER

Hypothyroid group

Experimental hypothyroidism will be induced by administration of propylthiouracil for three weeks in the form of tablets diluted in water

OTHER

Hypothyroid group received exercise

Rats will be subjected to chronic swimming. The swimming protocol will consist of 8 weeks of low-intensity swimming exercise. The exercise groups will be adapted to a round water tank (70 cm × 70 cm) containing water at 28 ± 2°C for 3 days (10-45 min/day). The rats will then begin swimming, 45 min/day for the first two weeks at 10am and 60 min/day for the last six weeks at 10am

Sponsors & Collaborators

  • Riphah International University

    lead OTHER

Principal Investigators

  • Shazia Ali, PhD · Riphah International University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Weeks
Max Age
8 Weeks
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-20
Primary Completion
2022-01-30
Completion
2022-01-30

Countries

  • Pakistan

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06699069 on ClinicalTrials.gov